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Clinical Research & Trial Matching

Support Beyond Our Testing Portfolio

Leverage our molecular information through our clinical research and trial matching services to help inform treatment decisions for your patients.

FoundationInsights® is a secure web-based application that provides access to data within high volume institutions for research use, pulled from our FoundationCore® knowledge base. FoundationInsights lets you query your population of patients with a variety of genomic and biomarker criteria to highlight disease and gene prevalence trends.

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Foundation Medicine matches patients to precision oncology trials based on genomic alterations, tumor type, and age. Our team of expert curators and genomicists helps facilitate awareness of genomically matched clinical trial options for your patients.
Our bioinformatics systems pull together basic trial information from public sources, scientific annotations curated by our expert team, and genomic findings through our comprehensive genomic profiling tests to identify trial options based on molecular match, evidence of potential benefit, and proximity to the nearest enrolling site.

Trial Matching Features

Precision Outreach

When patients with rare findings are matched to a partner clinical trial, our medical team reaches out to the ordering physician.

NCI – MATCH

When patients are genomically matched to an arm of the NCI-MATCH trial¹, physicians enrolled in digital reporting will be notified directly.

Just-in-Time Trial Networks

We partner with service providers who can open sites as soon as a patient is identified by the Precision Enrollment program.

How It Works

Precision Enrollment

Our Precision Enrollment program identifies patients with specific biomarkers and matches them with sponsor trials using the FoundationSmartTrials™ engine.

1

Gather Insights

Thousands of new genomic profiles are typically added to our FoundationCore® knowledgebase per week.

2

Match Patients

We identify patient profiles with rare findings, match them to available trials, and arrange for outreach.

3

Precision Outreach

Our team of consulting oncologists reaches out to the ordering physician and provides relevant clinical trial options.

4

Determine Interest

The physician determines the level of interest and is connected to the clinical trial sponsor or enrolling site to pursue enrollment.

5

Begin Enrollment

The sponsor provides the physician with enrollment options for their patient.

Foundation Medicine & Optimal Case Study

Our partnership with Optimal Research® enables speedy clinical trial enrollment. This partnership allowed us to coordinate all required steps for activation of a Just-In-Time trial site for a patient with a rare NSCLC biomarker, allowing the patient to enroll and receive the study drug within 12 business days of trial-site discussion with provider.

Benefits for Providers and Their Patients

  • Patients can now be identified for trials that were previously unavailable to them due to geographical constraints.

  • With successful patient matching, the clinical trial can be delivered to the patient in time to fit within their treatment regimen.

  • Patient matching provides additional screening support for trial sites.

Additional Notes

1National Cancer Institute (NCI). (2015, June - ). Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial). Identifier NCT02465060. Retrieved from https://clinicaltrials.gov/ct2/show/NCT02465060

We Have Even More to Offer

Learn more about our comprehensive genomic profiling tests or explore our decision support or online ordering and report integration services.